A putative ABC transporter confers durable resistance to multiple fungal pathogens in wheat
Krattinger SG, Lagudah ES, Spielmeyer W, Sing RP, Huerta-Espino J, McFadden H, Bossolini E, Selter LL and Keller B (2009) A putative ABC transporter confers durable resistance to multiple fungal pathogens in wheat.Science 323: 1360-1363.
Agricultural crops benefit from resistance to pathogens that endures
over years and generations of both pest and crop. Durable disease
resistance, which may be partial or complete, can be controlled by
several genes. Some of the most devastating fungal pathogens in wheat
are leaf rust, stripe rust, and powdery mildew. The wheat gene Lr34 has supported resistance to these pathogens for more than 50 years. Lr34
is now shared by wheat cultivars around the world. Here, we show that
the LR34 protein resembles adenosine triphosphate–binding cassette
transporters of the pleiotropic drug resistance subfamily. Alleles of Lr34 conferring resistance or susceptibility differ by three genetic polymorphisms. The Lr34 gene, which functions in the adult plant, stimulates senescence-like processes in the flag leaf tips and edges.